Endocrine Abstracts

Gliomas constitute the most frequent type of brain tumors and are characterized by a rapid growth and high diffusion through the brain. In particular, astrocytomas are a subtype of malignant gliomas that are graded from low to high aggressiveness (i.e. grade I, II, III and IV), being grade IV (glioblastoma multiforme, GBM) the most malignant type, and one of the most common cancers in the brain and CNS. To date, surgery is the first-line therapy combined with chemotherapy or r...